2007 Pauling Medal
Award Symposium is Saturday, November 17th
Symposium Chair
Dr. Richard L Nafshun
Dept. of Chemistry
Oregon State University University
nafshunr@chem.orst.edu
Tel: 541.737.6742
Fax: 541.737.2062
Award Chair
Dr. Glenn T. Evans
Dept. of Chemistry
Oregon State University
Tel: 541.737.6717
Fax: 541.737.2062
Recognizing outstanding accomplishments in chemistry in the spirit of and in honor of Linus Pauling, a native of the Pacific Northwest
The 2007 Linus Pauling Medal will be awarded to Jacqueline K. Barton, ,the Arthur and Marian Hanisch Memorial Professor at the Department of Chemistry, California Institute of Technology
The Linus Pauling Medal is given annually by the Oregon, Portland and Puget Sound Sections of the American Chemical Society. The award recognizes outstanding accomplishments in chemistry in the spirit of and in honor of Linus Pauling, a native of the Pacific Northwest.
Symposium
The 2007 Award symposium is Saturday, November 17th on the campus of Oregon State University. Details (time and place) will be made available here.
About the 2007 Pauling Medalist
Dr. Jacqueline K. Barton is the Arthur and Marian Hanisch Memorial Professor of Chemistry at the California Institute of Technology. She is a native New Yorker. Barton was awarded the A.B. summa cum laude at Barnard College in 1974 and a Ph.D. in Inorganic Chemistry at Columbia University in 1978 in the laboratory of S. J. Lippard. After a postdoctoral fellowship at Bell Laboratories and Yale University with R. G. Shulman, she became an assistant professor at Hunter College, City University of New York. In 1983, she returned to Columbia University, becoming an associate professor of chemistry and biological sciences in 1985 and professor in 1986. In the fall of 1989, she joined the faculty at Caltech.
Professor Barton has pioneered the application of transition metal complexes to probe recognition and reactions of double helical DNA. She has designed chiral metal complexes that recognize nucleic acid sites with specificities rivaling DNA-binding proteins. These synthetic transition metal complexes have been useful in elucidating fundamental chemical principles that govern the recognition of nucleic acids, in developing luminescent and photochemical reagents as new diagnostic tools, and in laying a foundation for the design of novel chemotherapeutics. Most recently, her research group has designed bulky metallointercalators as site-specific probes of DNA base mismatches. These complexes are now being applied in the discovery of single base mutations and in new diagnostic and chemotherapeutic strategies targeted to mismatch repair deficient cells. Barton has also carried out seminal studies to elucidate electron transfer chemistry mediated by the DNA double helix. She first showed that oxidative damage to DNA can arise from a distance through charge migration through the DNA duplex. She furthermore established that DNA charge transport chemistry is exquisitely sensitive to intervening perturbations in the DNA base stack, as with single base mismatches or lesions. This chemistry has since been applied in the development of DNA-based electrochemical sensors for mismatches, lesions, and protein binding. Barton is now also focused on establishing where this chemistry is harnassed within the cell. DNA charge transport may provide a route for long range signaling among DNA-bound proteins and may be critical to understanding DNA damage and repair within the cell.
Barton has received numerous awards. These include the Alan T. Waterman Award of the National Science Foundation, the American Chemical Society (ACS) Award in Pure Chemistry, the ACS Eli Lilly Award in Biological Chemistry, ACS Garvan Medal, and the ACS Breslow Award in Biomimetic Chemistry. She has also received the ACS Baekeland Medal, the Fresenius Award, the ACS Tolman Medal, the Mayor of New York's Award in Science and Technology, the Havinga Medal, the Paul Karrer Medal, the ACS Nichols Medal, the Weizmann Women & Science Award, the ACS Gibbs Medal and the ACS Cotton Medal. She was a fellow of the Sloan Foundation, a Dreyfus Teacher-Scholar, and an NSF Presidential Young Investigator. She is a recipient of a prestigious MacArthur Foundation Fellowship and she has been elected to the American Academy of Arts and Sciences, the American Philosophical Society, and the National Academy of Sciences. She has received eight honorary doctorates including, most recently, Yale University. She also received university medals from Barnard College and Columbia University. She has, in addition, served the chemical community through her participation in ACS, governmental and industrial boards. Based upon her industrial board service, she was named an Outstanding Director by ODX.
Linus Pauling
Linus Carl Pauling was born in Portland, Oregon, on February 28, 1901. He graduated from the Oregon Agricultural College in 1922 with a bachelor of science degree in chemistry engineering. Three years later he received his Ph.D. in chemistry from the California Institute of Technology. After a year abroad, Dr. Pauling joined the Caltech faculty and remained there for over three decades. Following stints at the Center for the Study of Democratic Institutions, the University of California, San Diego, and Stanford University, he established the Linus Pauling Institute of Science and Medicine at the age of 72.
Linus Pauling was a brilliant chemist and an untiring political activist who received Nobel Prizes for chemistry and peace. He was awarded the Nobel Prize for Chemistry in 1954 for his chemical research which was centered on the themes of chemical bonding and molecular structure. Published in 1939, his book entitled The Nature of the Chemical Bond remains a landmark study which is still widely read and referenced. Dr. Pauling received the 1962 Nobel Prize for Peace. The award's citation acclaimed him for his work "not only against the testing of nuclear weapons, not only against the spread of these armaments, not only against their very use, but against all warfare as a means of solving international conflicts." Dr. Pauling was the recipient of numerous other awards, including the first Pauling Medal in 1966.
Linus Pauling Centenary Exhibit
Linus Pauling Nobel Award Biography
1966
Linus Pauling
Manfred Eigen
Herbert C. Brown
Henry Eyring
1970
Harold C. Urey
Gerhard Herzberg
E. Bright Wilson
E. J. Corey
Roald Hoffmann
Paul Bartlett
F. Albert Cotton
John A. Pople
Dudley Herschbach
Daniel Koshland
1980
John D. Roberts
Henry Taube
George Pimentel
Gilbert Stork
John S. Waugh
Harold Scheraga
Harry B. Gray
Harden McConnell
Keith Ingold
Neil Bartlett
1990
James P. Collman
Rudolph Marcus
Kenneth Wiberg
Richard N. Zare
James A. Ibers
Alexander Rich
Kyriacos Nicolaou
Ahmed H. Zewail
Allen J. Bard
Peter B. Dervan
2000
Gabor J. Somorjai
Tobin J. Marks
John Brauman
Robert H. Grubbs
Martin Karplus
George Whitesides
Peter Stang
Jacqueline K. Barton