Ionization processes, methodologies, and instrumentation employed in mass spectrometry are investigated in Dr. Barofsky's laboratory. Individual studies are structured around scientific problems in organic chemistry and biochemistry that require extensive use of mass spectrometry for their solution.

Associate Professor (Affiliate)  ·  Ph.D. Colorado School of Mines  ·  Jennifer A. Field

Dr. Field's research is focused on the fate and transport of organic chemicals in the environment. Current research centers on the occurrence and distribution of polar organic contaminants. One of the main focuses of the research program is on the use of field-based experimentation aimed at investigating the factors that control the occurrence and distribution of contaminants in the environment.

Our research is concerned with new methodology, techniques, and instrumentation for analytical chemistry. Currently most efforts are directed at development of chemical sensors and field instrumentation for environmental applications to evaluate redox chemistry, redox transformations, and chemical speciation in ground water samples. Primary analytical techniques in these studies include molecular absorption and luminescence spectrometry (fluorescence and chemiluminescence) and ICP emission spectrometry. Analytes of interest include Cr, As, Se, chloroform, TCE, H₂, and sulfide.

Assistant Professor  ·  Ph.D. Univeristy of Konstanz, Germany  ·  Claudia Maier

Central to our research is an eclectic approach. We combine chemical, bioanalytical and biophysical approaches for the structural and functional characterization of proteins and their interactions with other biomolecules. As part of these efforts we focus on the implementation of biomolecular mass spectrometry. Current projects involve the study of conformational properties of proteins, the assembly of protein complexes, and protein-protein interactions. Our functional proteomics efforts are in the areas of signal transduction, cardiovascular research and aging.

Vincent T. Remcho   ·  Associate Professor  ·  Ph.D. Virginia Tech

Our interest centers on unraveling the mechanics of separations and applying microscale chromatographic and electrophoretic techniques in bioanalytical chemistry and environmental analysis. To that end we study fluid flow in porous media, develop novel media for use in chromatography and electroseparations, study and harness molecular recognition processes involving natural and laboratory-produced specific binding agents (oligonucleotide "aptamers", oligopeptides, and others), and implement instruments in novel formats.  Lately this has led us to work on microfluidic, or lab-on-a-chip, devices.  The overarching goal of our work is to develop analytical methods that will allow for complex analyses - such as analysis of the proteome - to be conducted in as efficient a manner as possible.

Professor & Assistant Chairman  ·  Ph.D. Indiana University  ·    Michael W. Schuyler  

Professor Schuyler's interests involve applications of microcomputers to chemical research and teaching. His primary activity is selecting, designing, and implementing hardware and software for interfacing chemical instrumentation to microcomputers for data acquisition, data manipulation, and experimental control. His work involves cooperation with other faculty members and their research groups. He specializes in applications involving IBM PC-compatible computers.

Dr. Simonich’s research focuses on understanding regional and global atmospheric transport and deposition of anthropogenic semi-volatile organic compounds.  Field sites include the Olympic Penninsula of Washington, Marys Peak, Oregon, and seven U.S. National Parks. Analytes of interest include organochlorine pesticides, current use pesticides, polycyclic aromatic hydrocarbons, polybrominated diphenyl ethers, and fluorinated organic compounds. The research utilizes chromatography, mass spectrometry, and novel methods of sample extraction and purification.

John C. Westall    ·  Professor ·   Ph.D. Massachusetts Institute of Technology  ·   

Dr. Westall's research is focused on the application of surface and solution chemistry to problems in environmental chemistry, electrochemistry, and analytical chemistry. Current research topics include: (i) interactions of metal ions with heterogeneous environmental complexants; (ii) electrochemical processes in the environment, including corrosion and redox transformations of inorganic and organic pollutants; (iii) the processes that control the distribution of hydrophobic, ionogenic, and ionic organic compounds between water and environmental sorbents; (iv) electric double layer phenomena associated with environmental surfaces; (v) mathematical methods for the determination of equilibrium constants from experimental data; (vi) the application of multicomponent chemical equilibrium models to biogeochemical problems.